Vash Mugen

I'm not really big into these here Japanese cartoons, but this is one of the two that I really like. Trigun really throws off people that watch it. When it starts out, it's pretty funny as Vash takes on a series of fairly harmless and minor thugs and villains. If that's all you're looking for in the series, I wouldn't recommend watching the second half of the series.

Was Magenta On Blues Clues A Boy

The second half really gets dark in its viewpoints. It really shows that there's a human side as Vash fights with both his enemies and himself.

So if you're looking for some comedy and darker views on life, I'd really recommend Trigun.